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Q: Is basic immune strength important for preventing infection?

The term “immunity” is well known. When immune strength is weakened, the likelihood of viral infection and severe illness increases. This is easy to understand. In COVID-19 infections, the phenomenon of a cytokine storm has been observed. This occurs when the body is unable to suppress oxidative stress caused by the virus with its own immune system. In response, the body indiscriminately releases excessive amounts of cytokines, assuming they will help fight the virus.

However, when excessive cytokines are released, they not only target the virus but also cause damage to the lungs, liver, kidneys, and even the testes. Therefore, strengthening basic immunity is extremely important.

Q: Are individuals with pre-existing conditions or atopic dermatitis more likely to develop severe symptoms?

Individuals with pre-existing conditions are at a significantly higher risk of severe illness. However, a study analyzing the risk factors for severe illness and death during the 2009-2010 influenza pandemic did not list atopic dermatitis as a risk factor.

That said, since atopic dermatitis results from an imbalance in the immune system, it is always advisable to take precautions.

Q: What foods help boost immunity, and what should be avoided?

Foods known to reduce oxidative stress and enhance immune function are those with deep colors. For example, vegetables and fruits that are red or purple are believed to help lower oxidative stress.

Rather than focusing on beneficial foods, it is more important to avoid certain ones—specifically, sugars and carbohydrates. This is because elevated blood sugar levels are associated with increased oxidative stress. Therefore, it is advisable to minimize their consumption.

Q: What is a cytokine storm, which leads to severe illness?

A cytokine storm occurs when a COVID-19 infection leads to interstitial pneumonia and worsens significantly. The process involves the virus triggering oxidative stress, which then causes the excessive release of immune-related cytokines.

This reaction is similar to an allergic response. As the virus continues to multiply, the body perceives that releasing more cytokines will help combat the infection. However, excessive cytokine release does not just attack the virus—it also damages vital organs such as the lungs, liver, kidneys, and testes, leading to widespread complications.

For this reason, it is sometimes referred to as an “immune storm,” where an extreme immune reaction occurs, similar to severe allergies. The key is to implement effective treatment before such a severe cytokine storm develops.

※ The views expressed in this video and text reflect the personal opinions of Dr. Haruhiko Inubo, Special Appointment Professor at Gifu University’s Antioxidant Research Division, and do not represent the official stance of any affiliated institution.